Pure Encapsulations Nrf2 Detox

PureFormulas is an authorized retailer of Pure Encapsulations products. You can shop with confidence, knowing that all products purchased from PureFormulas are authentic, and sourced directly from the brand. Cruciferous vegetables of the Brassica family have long been recognized for their ability to support detoxification‚ thereby maintaining healthy cells and tissues. Cruciferous vegetables‚ like broccoli‚ cauliflower‚ Brussels sprouts and kale‚ are the richest sources of glucosinolates‚ which are considered to be the most bioactive constituents. Glucosinolates are converted in the body to isothiocyanates after they are ingested and hydrolyzed. The isothiocyanate sulforaphane is one of the most effective activators of phase II detoxification‚ which occurs primarily in the gut and the liver. Sulforaphane and resveratrol promote the activity of nuclear factor erythroid 2-related factor 2 (Nrf2)‚ a transcription factor that supports robust‚ long-lasting expression of numerous genes responsible for phase II detoxification and protection against oxidative stress. Among these genes are glutathione peroxidase‚ superoxide dismutase and various phase II enzymes‚ such as glutathione sulfotransferases. Nrf2 also supports expression of glutathione glutamylcysteinyl ligase‚ which is responsible for a critical step in the biosynthesis of glutathione‚ a vital component of cellular antioxidant and detoxification systems. Found in virtually every cell of the body glutathione plays essential roles in protein synthesis‚ synthesis and repair of DNA‚ enzyme function‚ transport and cell maturation. Optimal levels of glutathione have been associated with physical and mental health. The highest concentration of glutathione is found in the liver‚ where it offers antioxidant support‚ protects tissue and maintains detoxification. In a randomized clinical trial‚ supplementation with 250 and 1‚000 mg of Setria® glutathione per day increased glutathione levels in the blood after one‚ three and six months. At six months‚ mean glutathione levels in the high-dose group increased 30-35% in erythrocytes‚ plasma and lymphocytes‚ and 260% in buccal cells (p<0.05). In the low-dose group‚ mean glutathione levels increased 17% and 29% in blood and erythrocytes‚ respectively (p<0.05). Both glutathione dose groups showed support for antioxidant defenses‚ indicated by decreases in the oxidized-to-reduced-glutathione ratio in whole blood after six months.‡ Benefits & Features: • Supports phase II enzyme function in the gut and liver‚ supporting toxin elimination‡ • Promotes the activity of Nrf2 to support detoxification and protection against oxidative stress‡ • Bioavailable‚ clinically studied Setria® glutathione • Standardized to contain a minimum of 1‚000 mcg sulforaphane • Part of the PureGenomics® product line • Made with high-quality vegan ingredients backed by verifiable science These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition. Report incorrect product information